WESTPHAL'S TEST FOR LOCOMOTOR ATAXIA.

Locomotor Ataxia Complicating Labour

is accurately known as those bearing upon the nervous complications of pregnancy and parturition. On these grounds I have deemed it of sufficient importance to place on record the following case, although, obstetrically considered in the strictest sense of that word, it presented no special attraction:? J. B., primipara, the subject of this note, was a patient in the Royal Maternity Hospital du...

Locomotor patterns in cerebellar ataxia.

Several studies have demonstrated how cerebellar ataxia (CA) affects gait, resulting in deficits in multijoint coordination and stability. Nevertheless, how lesions of cerebellum influence the locomotor muscle pattern generation is still unclear. To better understand the effects of CA on locomotor output, here we investigated the idiosyncratic features of the spatiotemporal structure of leg mus...

A Surgical Treatment of Locomotor Ataxia

Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish.

Whether changes in neuronal excitability can cause neurodegenerative disease in the absence of other factors such as protein aggregation is unknown. Mutations in the Kv3.3 voltage-gated K(+) channel cause spinocerebellar ataxia type 13 (SCA13), a human autosomal-dominant disease characterized by locomotor impairment and the death of cerebellar neurons. Kv3.3 channels facilitate repetitive, high...

False-Positive Head-Impulse Test in Cerebellar Ataxia

The objective of this study was to compare the findings of the bedside head-impulse test (HIT), passive head rotation gain, and caloric irrigation in patients with cerebellar ataxia (CA). In 16 patients with CA and bilaterally pathological bedside HIT, vestibuloocular reflex (VOR) gains were measured during HIT and passive head rotation by scleral search coil technique. Eight of the patients ha...